Grilled Chicken Spinach Panini

Featured in: Gentle Morning Bakes

This Italian-American panini combines tender grilled chicken breasts, fresh baby spinach, creamy mozzarella and Parmesan, all bound together with fragrant garlic butter on crusty bread. The sandwich is pressed until golden and the cheese melts into every crevice, creating an irresistible warm sandwich.

Preparation takes just 30 minutes total, making it perfect for lunch or dinner. The chicken is grilled with Italian herbs to enhance flavor, while the garlic butter adds richness to the crusty bread exterior. Each bite delivers savory depth from the three-cheese combination and fresh spinach.

Updated on Sun, 18 Jan 2026 14:28:00 GMT
Golden-brown Grilled Chicken Spinach Panini with melted mozzarella and fresh spinach peeking out of crusty bread.  Save to Pinterest
Golden-brown Grilled Chicken Spinach Panini with melted mozzarella and fresh spinach peeking out of crusty bread. | calmsukkar.com

The crunch of toasted bread meeting melted cheese has always been one of my favorite kitchen sounds. I started making these paninis on a rainy Tuesday when I had leftover grilled chicken and a craving for something warm and comforting. The garlic butter was a last-minute idea, and it turned out to be the best decision I made that week. Now it's my go-to lunch when I want something satisfying without spending an hour in the kitchen.

I made these for my sister one afternoon when she dropped by unexpectedly. She took one bite and declared it better than the cafe version she'd been buying every week. Watching her smile through melted mozzarella reminded me how good food doesn't need to be complicated. Sometimes the simplest combinations, done right, become the meals people remember.

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Ingredients

  • Boneless, skinless chicken breasts: Grilling them with Italian herbs creates juicy, flavorful slices that stay tender inside the panini, and letting them rest before slicing keeps all the moisture locked in.
  • Olive oil: Brushing the chicken before grilling prevents sticking and helps the seasonings cling to the meat.
  • Salt, black pepper, and dried Italian herbs: This simple trio brings out the natural flavor of the chicken without overpowering the other ingredients.
  • Unsalted butter: Softened butter blends easily with garlic and parsley, creating a spread that melts into the bread as it toasts.
  • Garlic cloves: Freshly minced garlic gives the butter a punchy, aromatic quality that makes every bite more interesting.
  • Fresh parsley: Chopped parsley brightens the garlic butter and adds a hint of freshness that balances the richness.
  • Rustic Italian or sourdough bread: Sturdy slices hold up to grilling and pressing without turning soggy, and the crust gets beautifully crispy.
  • Fresh baby spinach: Washing and drying the spinach well prevents extra moisture from making the bread steam instead of crisp.
  • Shredded mozzarella cheese: Melts into creamy, stretchy goodness that holds the sandwich together.
  • Grated Parmesan cheese: Adds a salty, nutty depth that mozzarella alone can't provide.
  • Olive oil for brushing: A light brush on the outside of the bread ensures even browning and a golden finish.

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Instructions

Get the grill ready:
Preheat your grill pan or outdoor grill to medium-high heat so it's hot enough to sear the chicken and lock in the juices. A properly heated surface prevents sticking and gives you those beautiful grill marks.
Season and grill the chicken:
Brush the chicken breasts with olive oil, then season generously with salt, pepper, and Italian herbs. Grill for five to six minutes per side until cooked through, let them rest for five minutes, and slice thinly so each piece fits neatly in the sandwich.
Make the garlic butter:
In a small bowl, mix softened butter with minced garlic and finely chopped parsley until well combined. This spread will melt into the bread and infuse every bite with flavor.
Assemble the paninis:
Lay out your bread slices and spread garlic butter on one side of each. On the unbuttered side of four slices, layer the sliced chicken, spinach, mozzarella, and Parmesan, then top with the remaining bread slices with the buttered side facing out.
Press and toast:
Heat a panini press or large skillet over medium heat. Place the sandwiches in the press, or if using a skillet, weigh them down with a heavy pan, and cook for three to five minutes per side until the bread is golden and the cheese is melted and gooey.
Serve hot:
Slice each panini in half and serve immediately while the cheese is still stretchy and the bread is at its crispiest. The warmth and aroma are half the experience.
A warm, savory Grilled Chicken Spinach Panini pressed to perfection, served alongside a simple green salad.  Save to Pinterest
A warm, savory Grilled Chicken Spinach Panini pressed to perfection, served alongside a simple green salad. | calmsukkar.com

One evening I made these paninis for a small dinner with friends, and we ended up eating them on the porch with cold lemonade. The conversation stretched long into the night, and I realized the best meals aren't always about fancy recipes. Sometimes it's just warm bread, melted cheese, and the people you share it with.

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Choosing Your Bread

The bread you pick makes a huge difference in how the panini holds up under heat. I've tried soft sandwich bread before, and it turned limp and soggy under the press. Rustic Italian or sourdough with a sturdy crust gives you that satisfying crunch on the outside while staying soft enough inside to soak up the garlic butter. Look for loaves with a tight crumb that won't fall apart when you slice them.

Variations to Try

Once you've made the classic version, it's fun to play around with what goes inside. I've swapped turkey for chicken, added roasted red peppers for a sweet smoky note, and even layered in thin tomato slices when they're in season. Provolone works beautifully in place of mozzarella if you want a sharper flavor. The garlic butter stays the same, it's the constant that ties everything together no matter what else you change.

Serving Suggestions

These paninis are hearty enough to stand alone, but pairing them with something light makes the meal feel complete. A simple green salad with lemon vinaigrette cuts through the richness of the cheese, and a bowl of tomato soup on the side turns lunch into something cozy and nostalgic. I've also served them with pickles and kettle chips for a more casual vibe.

  • Pair with a crisp arugula salad dressed in balsamic vinaigrette for a peppery contrast.
  • Serve alongside tomato basil soup for dipping and extra comfort.
  • Add a handful of pickles or olives on the side for a tangy, briny bite between panini halves.
Juicy grilled chicken and garlic butter spread inside a toasted Grilled Chicken Spinach Panini on rustic Italian bread. Save to Pinterest
Juicy grilled chicken and garlic butter spread inside a toasted Grilled Chicken Spinach Panini on rustic Italian bread. | calmsukkar.com

There's something deeply satisfying about biting into a panini you made yourself, with crispy edges, melted cheese, and that garlicky aroma rising up with the steam. I hope this becomes one of your easy favorites, the kind of recipe you turn to when you want comfort without fuss.

Recipe Questions

β†’ Can I use a regular skillet instead of a panini press?

Yes, absolutely. Place the assembled sandwich in a skillet over medium heat and use a heavy pan or cast iron skillet on top to weigh it down. Cook 3-5 minutes per side until golden and cheese melts.

β†’ How do I keep the chicken moist while grilling?

Pound the chicken breasts to even thickness before grilling to ensure uniform cooking. Avoid overcooking by checking for an internal temperature of 165Β°F. Let the chicken rest for 5 minutes after grilling before slicing.

β†’ What cheeses work best for this sandwich?

Mozzarella and Parmesan are the classic choice, but provolone, fontina, or a mix of Italian cheeses work wonderfully. Choose cheeses that melt smoothly for the best texture.

β†’ Can I prepare the components ahead of time?

Yes, grill the chicken and prepare the garlic butter up to 4 hours in advance. Store chicken refrigerated and bring to room temperature before assembling. Assemble the panini just before pressing and cooking for best results.

β†’ What bread works best for panini?

Rustic Italian, sourdough, or ciabatta breads are ideal. They have sturdy crusts that hold up to pressing and melting cheese. Avoid soft breads that compress too easily.

β†’ How can I add more vegetables to this panini?

Layer in sliced tomatoes, roasted red peppers, sun-dried tomatoes, or caramelized onions. Add these on top of the spinach to prevent the bread from becoming too moist.

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Grilled Chicken Spinach Panini

Warm panini with grilled chicken, fresh spinach, melty mozzarella, and garlic butter pressed to golden perfection.

Prep Duration
15 minutes
Cook Duration
15 minutes
Overall Time
30 minutes
Created by Elaine Mercer


Skill Level Easy

Cuisine Type Italian-American

Total Yield 4 Serving Size

Diet Needs None specified

List of Ingredients

Chicken

01 2 boneless, skinless chicken breasts
02 1 tablespoon olive oil
03 0.5 teaspoon salt
04 0.5 teaspoon black pepper
05 0.5 teaspoon dried Italian herbs

Garlic Butter

01 3 tablespoons unsalted butter, softened
02 2 cloves garlic, minced
03 1 tablespoon fresh parsley, finely chopped

Panini Assembly

01 8 slices rustic Italian or sourdough bread
02 2 cups fresh baby spinach, washed and dried
03 1.5 cups shredded mozzarella cheese
04 0.5 cup grated Parmesan cheese
05 Olive oil for brushing

How-To Steps

Step 01

Prepare grill surface: Preheat grill pan or outdoor grill to medium-high heat.

Step 02

Grill chicken breasts: Brush chicken breasts with olive oil and season with salt, pepper, and dried Italian herbs. Grill for 5 to 6 minutes per side until cooked through. Allow to rest for 5 minutes, then slice thinly.

Step 03

Prepare garlic butter mixture: Combine softened butter, minced garlic, and finely chopped parsley in a small bowl. Mix until well incorporated.

Step 04

Butter bread slices: Arrange bread slices on work surface. Spread garlic butter mixture on one side of each slice.

Step 05

Build panini sandwiches: On the unbuttered side of 4 bread slices, layer sliced grilled chicken, fresh spinach, mozzarella cheese, and Parmesan cheese. Top with remaining bread slices, buttered side facing outward.

Step 06

Toast panini: Heat panini press or large skillet over medium heat. Place sandwiches in press or skillet, using a heavy pan to weigh down if necessary. Cook 3 to 5 minutes per side until bread is golden brown and cheese is melted.

Step 07

Finish and serve: Slice panini diagonally in half and serve immediately while hot.

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Tools Needed

  • Grill pan or outdoor grill
  • Panini press or large skillet
  • Mixing bowl
  • Sharp knife and cutting board

Allergy Details

Review the ingredients for any allergens and consult your doctor with concerns.
  • Contains wheat from bread
  • Contains milk from cheese and butter
  • May contain traces of gluten and dairy; verify bread and cheese labels for allergen concerns

Nutrition Per Serving

These nutrition details are for reference only and don’t take the place of professional advice.
  • Caloric Value: 450
  • Fats: 20 g
  • Carbohydrates: 35 g
  • Proteins: 32 g

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